Manasi Bhavsar, Naman Mangukia, Archana Mankad, Toral Manvar
Tobacco
kills their half of the consumers still, grown as the most lucrative crop
worldwide for different uses like chewing, smoking, and snuffing. On the other
side, it was known as a chief medicinal plant by Native Americans, ancient
European, Amazonian and Indian. In the middle 20th century tobacco was declared
a negative and hazardous plant because of its nicotine component. Nicotiana
tabacum (N. tabacum) is well studied in plant biotechnology and
studied as a model plant. Likewise. N. tabacum miRNAs were also identified a
decade ago however a genome-wide computational approach to identify miRNAs
remained to be explored. These XenomiRs and their cross-species talk were also
revealed for the first time in the current study. The top ten hub nodes (CCNE1,
DDX5, NEUROD1, SOS1, CUL2, OPHN1, SOX9, KCNA1, FBXW2, and NOC3L)
were retrieved from the experiment which gives evidence of tobacco miRNAs and
their involvement in diseases like carcinoma and neurodevelopmental disorders.
Nicotiana
tabacum (Tobacco),
miRNAs, Genome-wide analysis, Human health
VOL.14, ISSUE No.1, March 2022